MovDisordV3, Main, Exploration, bibRecord, 000288

Colonic bacterial composition in Parkinson's disease.

Identifieur interne : 000288 ( Main/Exploration ); précédent : 000287; suivant : 000289

Colonic bacterial composition in Parkinson's disease.

Auteurs : Ali Keshavarzian [États-Unis] ; Stefan J. Green [États-Unis] ; Phillip A. Engen [États-Unis] ; Robin M. Voigt [États-Unis] ; Ankur Naqib [États-Unis] ; Christopher B. Forsyth [États-Unis] ; Ece Mutlu [États-Unis] ; Kathleen M. Shannon [États-Unis]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.

RBID : pubmed:26179554

Abstract

We showed that Parkinson's disease (PD) patients have alpha-synuclein (α-Syn) aggregation in their colon with evidence of colonic inflammation. If PD patients have altered colonic microbiota, dysbiosis might be the mechanism of neuroinflammation that leads to α-Syn misfolding and PD pathology.

DOI: 10.1002/mds.26307
PubMed: 26179554

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">We showed that Parkinson's disease (PD) patients have alpha-synuclein (α-Syn) aggregation in their colon with evidence of colonic inflammation. If PD patients have altered colonic microbiota, dysbiosis might be the mechanism of neuroinflammation that leads to α-Syn misfolding and PD pathology.</div>
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Movement Disorders (revue)

Colonic bacterial composition in Parkinson's disease.

Colonic bacterial composition in Parkinson's disease.

Source :

Abstract

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